学习经历
1996-2000 河北大学,学士
2001-2004 河北大学,硕士
2008-2015 河北农业大学,博士
工作经历
2005-2008 大阳城集团娱乐app网址下载,助教
2009-2012 大阳城集团娱乐app网址下载,讲师
2014-2022 大阳城集团娱乐app网址下载,副教授
2018-2019 中佛罗里达大学化学系,访问学者
2023- 大阳城集团娱乐app网址下载,教授
教学工作
本科生课程:
1.专业基础课《药物化学》、《天然药物化学》
2.专业拓展课《药物合成工艺学》
研究生课程:
《药学综合大实验》
主要研究方向及领域
木质纤维素是地球上储量最大的可再生生物质,其资源化利用对能源、环境以及农业可持续发展等方面都具有至关重要的意义。微生物降解与转化是生物质资源高值化利用的重要途径。目前的研究方向主要包括:
1.木质纤维素生物质的微生物降解、转化与利用。
2.芽孢杆菌降解木质素的机制研究。
主持课题项目
1.河北省自然科学基金生物农业联合基金,木质素降解优先在全株玉米青贮中的应用及调控机制研究,2023-2025,C2023204251,主持
2.河北省自然科学基金,解淀粉芽孢杆菌对β-O-4木质素的定向降解,2020-2022,C2020204149,主持
3.河北省重点研发计划,秸秆木质纤维素饲料化高效利用关键技术与应用示范, 2020-2022,20322909D,主持
代表性学术成果
研究论文(*通讯作者):
1.Xiaodan Li, Tongguo Gao, Yaru Zhang, Xinran Yu, Quan Wang, Shuna Li, Shuxiang Wang, Lijie Gao, Hongya Li*. Genomic characterization and proteomic analysis of Bacillus amyloliquefaciens in response to lignin, International Journal of Biological Macromolecules, 2024, 281, 136611.
2.Xiaodan Li, Zhuofan Li, Ming Li, Jingwen Li, Quan Wang, Shuxiang Wang*, Shuna Li, Hongya Li*. Transcriptomic and metabolomic analysis reveals the influence of carbohydrates on lignin degradation mediated by Bacillus amyloliquefaciens. Frontiers in Microbiology. 2024, 15:1224855.
3.Katelyn B. Bobek, Nameer S. Ezzat, Brandon S. Jones, Yujia Bian, Thomas E. Shaw, Titel Jurca, Hongya Li*, Yu Yuan*. Total synthesis of polysubstituted γ‑butyrolactone lignans 2(-)-hinokinin, (-)-bicubebin B, and (-)-isodeoxypodophylloto-xin 3 via oxime carbonate formation. Organic Letter, 2022, 25(1): 31-36.
4.Jing Ren, Xiaodan Li, Weitao Zhang, Zhuofan Li, Quan Wang, Shuna Li, Shuxiang Wang, Hongya Li*. Evaluation of application potential of dye-decolorizing peroxidase from Bacillus amyloliqueficiens in bioremediation of paper and pulp mill effluent. Frontiers in Microbiology, 2022, 13:1031853, 202210.
5.Jing Ren, Jingjing Huo, Quan Wang, Ze Liu, Shuna Li, Shuxiang Wang, Weiting Guo, Hongya Li*. Characteristics of immobilized dye-decolorizing peroxidase from Bacillus amyloliquefaciens and application to the bioremediation of dyeing effluent. Biochemical Engineering Journal, 2022, 182, 108430
6.Yaru Zhang, Jing Ren, Quan Wang, Shuxiang Wang, Shuna Li, Hongya Li*. Oxidation characteristics and degradation potential of a dye-decolorizing peroxidase from Bacillus amyloliquefaciens for crystal violet dye, Biochemical Engineering Journal, 2021, 168: 0-107930.
7.Juan Yang, Yaru Zhang, Shuo Wang, Shuna Li, Yiding Wang, Shuxiang Wang, Hongya Li*. Biodegradation of crystal violet mediated by CotA from Bacillus amyloliquefaciens. Journal of Bioscience and Bioengineering, 2020, 130(4): 347-351.
8.Juan Yang, Tongguo Gao, Yaru Zhang, Shuo Wang, Hongya Li*, Shuna Li, Shuxiang Wang. Degradation of the phenolic beta-ether lignin model dimer and dyes by dye-decolorizing peroxidase from Bacillus amyloliquefaciens. Biotechnology Letters, 2019, 41 (8-9): 1015-1021.
9.Juan. Yang , Mengya Gao, Meng Li, Zhuozhou Li, Hua Li, Hongya Li*. Bacillus amyloliquefaciens CotA degradation of the lignin model compound guaiacylglycerol-β- guaiacyl ether. Letters in Applied Microbiology, 2018, 67(5):491-496.
发明专利:
李红亚, 李术娜, 王树香. 解淀粉芽孢杆菌MN-13及其应用. ZL 2021 1 0450872.8, 2022-10-25.