学习经历
2000-2004 中国矿业大学,学士
2004-2007 北京师范大学,硕士
2010-2017 河北农业大学,博士
工作经历
2007-2009 河北农业大学制药工程系,助教
2009-2014 河北农业大学制药工程系,讲师
2014- 河北农业大学生物医药系,副教授
2018-2019 美国加州大学戴维斯分校,访问学者
教学工作
本科生课程:
1. 专业必修课《生物分离工程》、《生物制药工艺学》
2. 专业选修课《微生物工程》
研究生课程:
1.发酵工程
主要研究方向及领域
农作物和林木的病害大发生,常使国家经济和人民生活遭受严重损失;有些患病作物能引起人畜中毒;一些优质高产品种往往因病害严重而被淘汰。目前的研究方向主要包括:
1.植物病原细菌基因组学。
2.植物病害绿色防控。
主持课题项目
1.河北省农业科技成果转化资金项目,防治根腐病枯草芽孢杆菌菌剂高效生产及示范应用,2024-2025,202460103030017,主持。
2.河北省自然科学基金生物农业联合基金培育项目,枯草芽孢杆菌防控全株玉米青贮饲料腐败变质的作用机制,2023-2025,C2023204044,主持。
代表性学术成果
研究论文(*通讯作者):
1.Zhaosha Liu, Jizong Zhang, Chenxi Fan, Shangyi Sun, Xutong An, Yanheng Sun, Tongguo Gao, Dongdong Zhang*. Influence of Bacillus subtilis strain Z-14 on microbial ecology of cucumber rhizospheric vermiculite infested with fusarium oxysporum f. sp. cucumerinum. Pesticide Biochemistry and Physiology, 2024, 201:105875.
2.Jiawen Xiao, Shangyi Sun, Zhaosha Liu, Chenxi Fan, Baocheng Zhu, Dongdong Zhang*. Analysis of key genes for the survival of Pantoea agglomerans under nutritional stress. International Journal of Biological Macromolecules, 2023, 253:127059.
3.Zhaosha Liu, Chenxi Fan, Jiawen Xiao, Shangyi Sun, Tongguo Gao, Baocheng Zhu, Dongdong Zhang*. Metabolomic and transcriptome analysis of the inhibitory effects of Bacillus subtilis strain Z-14 against Fusarium oxysporum causing vascular wilt diseases in cucumber. Journal of Agricultural and Food Chemistry, 2023, 71:2644–2657.
4.Jiawen Xiao, Zhaosha Liu, Shangyi Sun, Chenxi Fan, Dongmei Wang, Dongdong Zhang*. Complete Genome Sequence of Pantoea agglomerans CHTF15, a Walnut Pathogen. Molecular Plant-Microbe Interactions, 2023, 36(2):134–137.
5.Liu Zhaosha, Xiao Jiawen, Zhang Xuechao, Dou Shijuan, Gao Tongguo, Wang Dongmei, Zhang Dongdong*. Influence of Bacillus subtilis strain Z-14 on microbial communities of wheat rhizospheric soil infested with Gaeumannomyces graminis var. tritici. Frontiers in Microbiology, 2022, 13:923242.
6.Jiawen Xiao, Xiaojun Guo, Xinlei Qiao, Xuechao Zhang, Xiaomeng Chen, Dongdong Zhang*. Activity of fengycin and iturin A isolated from Bacillus subtilis Z-14 on Gaeumannomyces graminis var. tritici and soil microbial diversity. Frontiers in Microbiology, 2021, 12:682437.
7.Xuechao Zhang, Xiaojun Guo, Cuihong Wu, Chengcui Li, Dongdong Zhang*, Baocheng Zhu*. Isolation, heterologous expression, and purification of a novel antifungal protein from Bacillus subtilis strain Z‑14. Microbial Cell Factories, 2020, 19:214.
发明专利:
1.张冬冬,朱宝成,高同国,郭晓军,陈晓萌。枯草芽胞杆菌、其制剂及其应用,CN: ZL 2018 1 0519314.0.
2.张冬冬,朱宝成,郭晓军,高同国。一种新型抗菌肽及其制备方法和应用,CN: ZL 2020 1 0157659.3.
3.张冬冬,肖嘉文,张学超,陈晓萌。一种防治果蔬根腐病的枯草芽孢杆菌Z-14菌株及其应用,CN: ZL 2021 1 0057405.9.
4.张冬冬,肖嘉文,刘兆厦,张学超。耐受农药酷拉斯的小麦根腐病生防枯草芽孢杆菌及应用,CN: ZL 2021 1 1361759.9.
5.张冬冬,肖嘉文,杨静,刘兆厦,樊晨曦,孙尚仪。巨大芽孢杆菌RL-126菌株在促进农作物秸秆腐熟中的应用,CN: ZL 2022 1 0717760.9.
6.张冬冬,肖嘉文,杨静,刘兆厦,樊晨曦,孙尚仪。一株胶质类芽孢杆菌HB-02菌株及其促作物生长的应用,CN: ZL 2022 1 0717763.2.